产品货号：
Z26333
中文名称：
SERCA2/ATP2A2抗体
英文名称：
Anti-SERCA2/ATP2A2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SERCA2/ATP2A2 Antibody |
| 指标别名 | ATP2A2;ATP2B;Calcium pump 2;DAR;DD;DKFZp686P0211;FLJ20293;FLJ38063;SERCA2;SERCA2;ATP2A2;SERCA2b;SR Ca(2+) ATPase 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC,WB |
| 基因名称 | ATP2A2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human SERCA2 ATPase(665-679aa QRDACLNARCFARVE),identical to the related rat and mouse sequences. |
| 实际分子量 | 115KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SERCA2(SARCOPLASMIC RETICULUM Ca(2+)-ATPase 2),also called ATP2A2,ATP2B,encodes one of the SERCA Ca(2+)-ATPases,which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells.They are closely related to the plasma membrane Ca(2+)-ATPases,or PMCAs.SERCA2 belongs to the large family of P-type cation pumps that couple ATP hydrolysis with cation transport across membranes.The SERCA2 gene is mapped on 12q24.11.SERCA2 was expressed in all specimens,with pronounced expression in the subnuclear aspect of basal epidermal keratinocytes.There was variable suprabasal expression.SERCA2 expression was also observed in the infundibulum and outer root sheath of hair follicles;germinative and mature cells of sebaceous glands;secretory coil and duct of eccrine glands;apocrine gland cells;and arrector pili muscle.In Darier disease skin,strong SERCA2 positivity was detected in the basal,suprabasal,and acantholytic lesional cells.Perilesional Darier disease skin was comparable to normal skin. |
| Uniprot ID | P16615 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | ATPase,Ca++ transporting,cardiac muscle,slow twitch 2 |
| 蛋白名全称 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2(SERCA2/SR Ca(2+)-ATPase 2) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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